Endocrine Abstracts

Background: Levothyroxine replacement for hypothyroidism is safe and effective but may be associated with reduced quality of life and serious adverse effects if administered inappropriately. We set out to investigate if thyroid hormone profiles in hospitalised patients on levothyroxine are similar to those in inpatients without pre-existing thyroid dysfunction.Methods: We conducted a cross-sectional study in patients admitted for non-endocrine reasons to...

Background: Hyperthyroidism often runs an indolent course and may be undiagnosed for prolonged periods. Most patients are treated in the outpatient setting and the effects of hyperthyroidism on hospitalised patients are poorly studied. We set out to determine the prevalence of hyperthyroidism in a large cohort of inpatients and evaluated their comorbidities, reasons for hospitalisation and rehospitalisation rates.Methods: A case-control study was conduct...

Routine thyroid function testing (TFT) in hospitalised patients is not recommended; however, delayed management of thyroid dysfunction may have significant consequences. We quantified the rate of TFT in hospitalised patients and identified factors influencing the likelihood of finding significantly abnormal TSH (<0.01 or >10 mUI). TFTs were performed during 26 937/280 000 (9.6%) admissions between 2007 and 2011. 57.6% of those tested were female and mean age was 63.8 (...

Thyroid dysfunction is common and the clinical presentation of subjects with abnormal thyroid hormone concentrations varies widely. Whilst acute illness may affect the interpretation of thyroid function tests, delaying diagnosis and treatment of thyroid dysfunction may have significant consequences. We set out to determine the likelihood of thyroid function testing and the factors influencing the probability of serum TSH measurement in hospitalised patients with a recorded dia...